Remodelin hydrobromide

CAS No. 1622921-15-6

Remodelin hydrobromide ( Remodelin HBr; Remodelin Hydrobromide )

Catalog No. M12394 CAS No. 1622921-15-6

A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 47 In Stock
10MG 71 In Stock
25MG 133 In Stock
50MG 236 In Stock
100MG 353 In Stock
500MG 797 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Remodelin hydrobromide
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules.
  • Description
    A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules; significantly reduces the prevalence of misshapen nuclei in HGPS cells, prevents FTI-induced nuclear shape defects in normal fibroblasts and U2OS cells; does not affect Golgi apparatus integrity or tubulin polymer assembly, and does not cause cells to accumulate in mitosis.
  • Synonyms
    Remodelin HBr; Remodelin Hydrobromide
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    acetyl-transferaseNAT10
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    1622921-15-6
  • Formula Weight
    363.28
  • Molecular Formula
    C15H15BrN4S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 44 mg/mL
  • SMILES
    N#CC1=CC=C(C2=CSC(N/N=C3CCCC/3)=N2)C=C1.[H]Br
  • Chemical Name
    Benzonitrile, 4-[2-(2-cyclopentylidenehydrazinyl)-4-thiazolyl]-, hydrobromide (1:1)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Larrieu D, et al. Science. 2014 May 2;344(6183):527-32.
2. Mathieu J, et al. Cell Stem Cell. 2016 Jul 7;19(1):3-4.
3. Cobb AM, et al. Aging Cell. 2016 Jul 27. doi: 10.1111/acel.12506.
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