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Remodelin hydrobromide
CAS No. 1622921-15-6
Remodelin hydrobromide ( Remodelin HBr; Remodelin Hydrobromide )
Catalog No. M12394 CAS No. 1622921-15-6
A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 47 | In Stock |
|
| 10MG | 71 | In Stock |
|
| 25MG | 133 | In Stock |
|
| 50MG | 236 | In Stock |
|
| 100MG | 353 | In Stock |
|
| 500MG | 797 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRemodelin hydrobromide
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NoteResearch use only, not for human use.
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Brief DescriptionA potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules.
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DescriptionA potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules; significantly reduces the prevalence of misshapen nuclei in HGPS cells, prevents FTI-induced nuclear shape defects in normal fibroblasts and U2OS cells; does not affect Golgi apparatus integrity or tubulin polymer assembly, and does not cause cells to accumulate in mitosis.
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SynonymsRemodelin HBr; Remodelin Hydrobromide
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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Recptoracetyl-transferaseNAT10
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number1622921-15-6
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Formula Weight363.28
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Molecular FormulaC15H15BrN4S
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 44 mg/mL
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SMILESN#CC1=CC=C(C2=CSC(N/N=C3CCCC/3)=N2)C=C1.[H]Br
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Chemical NameBenzonitrile, 4-[2-(2-cyclopentylidenehydrazinyl)-4-thiazolyl]-, hydrobromide (1:1)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Larrieu D, et al. Science. 2014 May 2;344(6183):527-32.
2. Mathieu J, et al. Cell Stem Cell. 2016 Jul 7;19(1):3-4.
3. Cobb AM, et al. Aging Cell. 2016 Jul 27. doi: 10.1111/acel.12506.
2. Mathieu J, et al. Cell Stem Cell. 2016 Jul 7;19(1):3-4.
3. Cobb AM, et al. Aging Cell. 2016 Jul 27. doi: 10.1111/acel.12506.
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